Definition

Stiff person syndrome (SPS) is an extremely rare progressive neurological disorder characterized by persistent rigidity and spasms of certain voluntary muscles, especially those of legs and feet. In some cases, muscles of the neck, trunk, and shoulders may also be involved. SPS may begin as recurring (intermittent) episodes of stiffness and spasms, often precipitated by surprise or minor physical contact.

Description

SPS is a rare progressive neurological disorder characterized by constant painful contractions and spasms of voluntary muscles, particularly the muscles of the back and upper legs. In 1956, scientists at the Mayo Clinic also coined the term stiff man syndrome, and clearly described the stiff person syndrome as a neurological disorder. The rigidity, which is characterized by tightness and stiffness, begins slowly over several months at the axial muscles, especially the thoracic and lumbar...