Definition

Leigh syndrome is an early onset, progressive neurological disease that involves defects in the normal function of the mitochondria. The mitochondrion is a small organelle located in most cells and is responsible for producing energy for cells and tissues throughout the body.

Description

Leigh syndrome is caused by defective cellular respiration that supplies many tissues with energy. The disorder is severe and can be particularly difficult for family members, as infants are among the severely affected. Leigh syndrome is also known as necrotizing encephalopathy.

Demographics

Leigh syndrome is a very rare disease that affects different peoples relatively equally. Some studies have shown that more males are affected than females.

Causes and symptoms

In Leigh syndrome, symptoms usually...