Thalidomide embryopathy
Definition
The term thalidomide embryopathy (TE) is used to describe a specific pattern of birth defects caused by a mother's use of the drug thalidomide during her pregnancy. The drug is able to cross the placenta and reaches the developing embryo, causing parts of the embryo's body to form abnormally. The most common birth defects observed in infants with TE include structural abnormalities of the arms, legs, ears, and eyes, although other organs may also be affected. The most harmful time to use thalidomide is during the first three to six weeks of pregnancy.
Description
Thalidomide was originally marketed in Germany in October 1957 as a safe, inexpensive, and effective sedative. Its use was later expanded to include treatment of insomnia, anxiety, upset stomach, and morning sickness during...
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