Li-Fraumeni syndrome
Definition
Li-Fraumeni syndrome (LFS) is a hereditary condition in which individuals have an increased risk for developing certain kinds of tumors. The characteristic tumors of LFS are adrenocortical carcinoma, breast cancer, brain cancer, leukemia and sarcoma. Li-Fraumeni syndrome has previously been known as the sarcoma, breast, leukemia and adrenal gland (SBLA) syndrome.
Description
Li-Fraumeni syndrome is an inherited condition that is associated with a significantly increased risk for developing certain kinds of cancer. It is classified as a hereditary cancer syndrome and was first described in 1969 by two physicians, Dr. Li and Dr. Fraumeni. Hereditary cancer syndromes typically result in multiple family...
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