Leukodystrophy

Definition

Leukodystrophy describes a collection of about 15 rare genetic disorders that effect the brain, spinal cord and peripheral nerves. It is characterized by imperfect growth or development of the white matter covering nerve fibers in the brain.

Description

Leukodystrophy comes from the Greek words leuko meaning white (referring to the white matter of the nervous system) and dystrophy meaning imperfect growth or development. The white matter is called the myelin sheath and is an extremely complex substance composed of at least 10, and probably more, chemicals. The myelin sheath protects the axon (a long and single-nerve cell process that acts as a wire to conduct impulses away from the...

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