Hemolytic-uremic syndrome

Definition

Hemolytic-uremic syndrome (HUS) is a syndrome defined by the presence of acute hemolytic anemia (low red blood cell count caused by the break up of red cells within the blood stream by a person's own immune system), thrombocytopenia (a low number of platelets), and kidney failure. Having these three symptoms all at once can be caused by a number of problems—some by infections, others by genes, and some are still unknown.

Description

About 90% of HUS cases occur in children less than five years of age. In most cases, there is an early phase of diarrhea, followed by the lowered blood counts and the renal failure. Most patients get better after HUS, a few die during the worst stage of the illness, others go on to have life-long kidney disease, and some will progress to having a...

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