Dentatorubral-pallidoluysian atrophy
Definition
Dentatorubral-pallidoluysian atrophy (DRPLA) is a disorder of ataxia (loss of balance), choreoathetosis (involuntary rapid, irregular, jerky movements or slow, writhing movements that flow into one another), and dementia (inability to clearly think; confusion, poor judgement; failure to recognize people, places, and things; personality changes) in adults, and ataxia, myoclonus (involuntary spasms of a muscle or muscle group), epilepsy (seizures), and loss of intellectual function (mental retardation) in children.
Description
DRPLA has also been referred to as Haw River syndrome and Natito-Oyanagi disease. The typical age of onset...
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