Adams-Oliver syndrome
Definition
Adams-Oliver syndrome (AOS) is a condition involving the combination of congenital scalp defects (called aplasia cutis congenita) and a specific type of limb defect.
Description
Adams-Oliver syndrome is a genetic condition characterized by aplasia cutis congenita, most commonly of the scalp and skull, and terminal transverse limb defects. Congenital heart disease has also been reported in individuals with this condition. The exact cause of the condition is not well-understood. There is extreme variability in the severity of problems between families with AOS.
Genetic profile
There have been both familial and non-familial cases of Adams-Oliver syndrome reported. The majority of genetic cases have been...
[The entire page is 1616 words long]