Oct 10, 2008

Encyclopedia of Children's Health | Down Syndrome

Definition

Down syndrome is the most common cause of mental retardation and malformation in a newborn. A genetic disorder, it occurs because of the presence of an extra chromosome.

Description

Chromosomes are units of genetic information that exist within every cell of the body. Twenty-three distinctive pairs, or 46 total chromosomes, are located within the nucleus (central structure) of each cell. When a baby is conceived by combining one sperm cell with one egg cell, the baby receives 23 chromosomes from each parent, for a total of 46 chromosomes. Sometimes, an accident in the production of a sperm or egg cell causes that cell to contain 24 chromosomes. This event is referred to as nondisjunction. When...

[The entire page is 3077 words long]

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